Meltem Müftüoğlu 2. Unvanı

EK-4
ÖZGEÇMİŞ
1. Adı Soyadı: Meltem Müftüoğlu
2. Unvanı: Profesör
3. Öğrenim Durumu:
Derece
Lisans
Yüksek Lisans
Doktora
Alan
Biyoloji
Biyokimya
Biyokimya
Üniversite
Orta Doğu Teknik Üniversitesi
Hacettepe Üniversitesi
Hacettepe Üniversitesi
Yıl
1991
1995
2001
4. Akademik Unvanlar
Yardımcı Doçent 2001 (Hacettepe Üniversitesi, Tıp Fakültesi, Biyokimya Anabilim Dalı)
Doçent 2005 (Biyokimya - YÖK)
Profesör 2015
Görev Yaptığı Üniversite ve Araştırma Enstitüleri
1. Hacettepe Üniversitesi, Tıp Fakültesi, Biyokimya Anabilim Dalı, Ankara (1993-2004)
2. National Institute of Health, National Institute on Aging, Laboratory of Molecular
Genetics, USA (04/1999-06/2000)
3. National Institutes of Health, National Institute on Aging, Laboratory of Molecular
Gerontology, USA (2003-2009)
4. University of Copenhagen, Faculty of Medicine, Department of Cellular and Molecular
Medicine, Center for Healthy Aging, Copenhagen, Denmark (2009-2011)
5. Koç Üniversitesi, Tıp Fakültesi, Tıbbi Biyokimya Anabilim Dalı, Istanbul (201107/2013)
6. Acıbadem Üniversitesi, Moleküler Biyoloji ve Genetik Bölümü, Istanbul (2014-
)
5. Yönetilen Yüksek Lisans ve Doktora Tezleri
5.1 Yüksek Lisans Tezleri
Tamamlanmış
1- Arın Doğan "İnsan Cockayne sendromu B proteininin NEIL1 enzim aktiviteleri üzerine
etkilerinin araştırılması", Hacettepe Üniversitesi-2008 (Eş Danışman).
2- Derya Aydın "Bitki tabanlı küçük molekül inhbitörlerinin kanser türleri üzerinde
potansiyel ekilerinin araştırılması", Koç Üniversitesi-2012 (Eş Danışman)
3- İlgü Ece Gülser “DNA polimeraz gama’ya bağlanan proteinlerin belirlenmesi ve kanser
üzerine etkilerinin araştırılması”, Acıbadem Üniversitesi- 2015 (Danışman).
6. Yayınlar
6.1 Uluslararası hakemli dergilerde yayınlanan makaleler
1. Ozer N, Muftuoglu M, and Ogus IH. A simple and sensitive method for the activity
staining of xanthine oxidase. J Biochem Biophys Methods, 36, 95-100, 1998.
2. Ozer N, Muftuoglu M, Ataman D, Ercan A, and Ogus IH. Simple, high-yield
purification of xanthine oxidase from bovine milk. J Biochem Biophys Methods, 39,
153-159, 1999.
3. Tuo J, Muftuoglu M, Chen C, Jaruga P, Selzer R, Brosh R, Rodriquez H, Dizdaroglu
M, and Bohr VA. The Cockayne syndrome group B gene product is involved in
general genome base excision repair of 8-hydroxyguanine in DNA. J Biol Chem, 276,
45772-45779, 2001.
4. Muftuoglu M, Selzer RR, Tuo J, Brosh RM Jr, and Bohr, V.A. Phenotypic
consequences of mutations in the conserved motifs of the putative helicase domain of
the human Cockayne syndrome group B gene. Gene, 283, 27-40, 2002.
5. Selzer RR, Nyaga S, Tuo J, May A, Muftuoglu M, Christiansen M, Citterio E, Brosh
RM Jr., and Bohr VA. Differential requirement for the ATPase domain of the
Cockayne syndrome group B gene in the processing of UV-induced DNA damage and
8-oxoguanine lesions in human cells. Nucleic Acids Res, 30, 782-93, 2002.
6. Muftuoglu M, Dalmizrak O, Elibol B, Ercan A, Kulaksiz G, Ogus H, Dalkara T, and
Ozer N. Mitochondrial complex I and IV dysfunction of leukocytes in Parkinson`s
Disease. Turk J Biochem, 28, 246-251, 2003.
7. Muftuoglu M, Elibol B, Dalmizrak O, Ercan A, Kulaksiz G, Ogus H, Dalkara T, and
Ozer N. Mitochondrial complex I and IV activities in leukocytes from patients with
parkin mutations. Movement Disorders, 19, 544-548, 2003.
8. Muftuoglu M, Wong K, Imam S, Wilson DM, Bohr VA, and Opresko PL. Telomeric
protein TRF2 interacts with base excision repair proteins and stimulates DNA
synthesis by DNA polymerase β. Cancer Research, 66(1),113-24, 2006.
9. Muftuoglu M, Sharma S, Thorslund T, Stevnsner T, Soerensen MM, Brosh RM and
Bohr VA. Cockayne syndrome group B protein has novel strand annealing and
exchange activities. Nucleic Acids Res, 34(1), 295-304, 2006.
10. Cheng WH, Muftuoglu M, and Bohr VA. Werner syndrome protein takes control of
DNA strand breaks in S-phase. Exp Gerontol, 42(9), 871-878, 2007.
11. Kusumoto R, Muftuoglu M, and Bohr VA. The role of WRN in DNA repair is
affected by post-translational modifications. Mech Aging Dev, 128(1), 50-57, 2007.
12. Wong HK, Muftuoglu M, Beck G, Imam SY, Bohr VA and Wilson DM. Cockayne
syndrome B protein stimulates apurinic endonuclease I activity and protects against
agents that introduce base excision repair intermediates. Nucleic Acids Res, 35(12),
4103-13, 2007.
13. Muftuoglu M, Kulikowicz T, Beck G, Lee JW, Piotrowski J, and Bohr VA. Intrinsic
ssDNA annealing activity in the C-terminal region of WRN. Biochemistry, 47(39),
10247-10254, 2008.
14. Cheng WH, Muftic D, Muftuoglu M, Dawut L, Morris C, Helleday T, Shiloh Y, and
Bohr VA. WRN is required for ATM activation and the S-phase checkpoint in
response to interstrand cross-link-induced DNA double-strand breaks. Mol Biol Cell,
19, 3923-3933, 2008.
15. Muftuoglu M, Oshima J, von Kobbe C, Cheng WH, Leistritz DF, and Bohr VA. The
clinical characteristics of Werner Syndrome: molecular and biochemical diagnosis.
Human Genet, 124, 369-377, 2008.
16. Stevnsner T, Muftuoglu M, Aamann MD, and Bohr VA. The role of Cockayne
Syndrome group B (CSB) protein in base excision repair and aging. Mech Ageing Dev,
129 (7-8), 441-448, 2008.
17. Muftuoglu M, Kusumoto R, Speina E, Beck G, Cheng WH and Bohr VA. Acetylation
regulates WRN catalytic activities and affects base excision repair. PLoS ONE, 3(4):114, 2008.
18. Ercan A, Kulaksiz G, Dalmizrak O, Muftuoglu M, Ogus H, Cavdar L, Inan L, and
Ozer N. Mitochondrial respiratory chain enzyme activities, mtDNA variants and gene
expression levels in Idiopathic Parkinson’s Disease. Turk J Biochem, 34, 97-104,
2009.
19. Muftuoglu M, de Souza-Pinto NC, Dogan A, Aamann M, Stevsner T, Rybanska I,
Kirkali G, Dizdaroglu M and Bohr VA. Cockayne syndrome group B protein
stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylase. J Biol Chem,
284(14), 9270-79, 2009.
20. De Souza-Pinto NC, Maynard S, Hashiguchi K, Hu J, Muftuoglu M, and Bohr VA
The recombination protein RAD52 cooperates with the excision repair protein OGG1
for the repair of 8-hydroxyguanine lesions. Mol Cell Biol, 29(16), 4441-54, 2009.
21. Aaman M, Sorensen M, Hvitby C, Berquist B, Muftuoglu M, Tian J, De Souza Pinto
N, Scheibye-Knudsen M, Wilson D, Stevnsner T, and Bohr VA. Cockayne syndrome
group B protein promotes mitochondrial DNA stability by supporting the DNA repair
association with the mitochondrial membrane. FASEB J, 24, 1-13, 2010.
22. Aamann MD, Muftuoglu M, Bohr VA, Stevnsner T. Multiple interaction partners for
Cockayne syndrome proteins: Implications for genome and transcriptome
maintenance. Mech Ageing Dev, 134 (5-6), 212-24, 2013.
23. Aamann MD, Hvitby C., Popuri V, Muftuoglu M, Lemminger L, Skeby C, Keijzers
G, Ahn B, Bjørås M, Bohr VA, and Stevnsner T. Cockayne Syndrome group B protein
stimulates NEIL2 DNA glycosylase activity. Mech Ageing Dev, 135, 1-14, 2014.
24. Muftuoglu M, Mori MP, de Souza Pinto NC. Formation and repair of oxidative
damage in the mitochondrial DNA. Mitochondrion, 17, 164-181, 2014.
6.2 Uluslararası bilimsel toplantılarda sunulan ve bildiri kitabında (Proceedings) basılan
bildiriler (SCI kapsamında)
1. Dalmizrak O, Muftuoglu M, Ogus IH, and Ozer N. The Effects of Glutathione
Depletion on Complex I Activity and Mitochondrial DNA in the Human
Leukocytes, European Journal of Biochemistry, 269 (S1), 44 , PS2-001, 2002.
2. Muftuoglu M, Selzer RR, Tuo J, Brosh RM Jr, and Bohr VA. Phenotypic
consequences of mutations in the conserved motifs of the putative helicase domain
of the human Cockayne syndrome group B gene. European Journal of
Biochemistry, 269 (S1), 41, PS1-024, 2002.
3. Dalmizrak O, Muftuoglu M, Atac B, Ogus IH, Ozer N and Elibol B. Mitochondrial
Complex I and Complex IV Activities in Lymphocytes from Patients with Parkin
Gene Mutations, Movement Disorders, 17 (S5), S62-S63, P164, 2002.
4. Opresko Pl., Muftuoglu M., Mason P., Wilson DM., and Bohr VA. RECQ
helicases and DNA repair pathways at telomeric DNA. Mutation
Research/Fundamental and Molecular Mechanisms of Mutagenesis, 577 (S1), 356,
2005.
5. Muftuoglu M., Kusumoto R., von Kobbe C., and Bohr VA. The Functional
Consequences of Acetylation on WRN protein. Mutation Research/Fundamental
and Molecular Mechanisms of Mutagenesis. 577 (S1), 345, 2005.
6. Muftuoglu M., Opresko P., and Bohr VA. Base excision repair pathway at
telomeric DNA. The FEBS Journal, 273 (S1), 54, OP-41, 2006.
7. Ercan A., Kulaksiz G., Muftuoglu M., Dalmizrak O., Ogus H, Cavdar L., Inan L.,
and Ozer N. Mitochondrial complex I and IV activities, ND2, ND4 gene mutations
and expressions in idiopathic Parkinson`s disease. The FEBS Journal, 273 (S1),
244-245, PP-622, 2006.
8. Muftuoglu M,. Aamann MD, Stevnsner T, Bohr VA. The involvement of
Cockayne syndrome B protein in Base Excision Repair. The FEBS Journal, 280
(S1), SW01.S3-29, 2013.
9. Oktem O, Muftuoglu M, Senbabaoglu F, Urman B. Real-time analysis of the
growth of human granulosa cells using an impedance-based signal processing
system: a new technology for translational research in human reproduction. Human
Reproduction, 28 (S1), i54-55, O-128, 2013.
10. Oktem O, Muftuoglu M, Senbabaoglu F, and Urman B. Real-time and quantitaive
assessment of the effects of different ovarian stimulation protocols on the
proliferation and cell cycle kinetics of granulosa cells using a new impedencebased system. Fertility and Sterility, 100 (3), S260, 2013.
11. Oktem O, Muftuoglu M, Senbabaoglu F, and Urman B. Effect of pharmacologic
inhibition of c-Jun N-terminal kinase (JNK) signaling pathway on cell proliferation
and cell cycle progression in human granulosa cell tumor. J Clinical. Oncology, 31
(15), S e22004, 2013.
12. Pamukcu C, Keskin N, Gulser IE, Erman B, Erman B, Uren A, Yakicier C,
Muftuoglu M. Identification and characterization of small molecule inhibitors
targeting DNA polymerase gamma for the treatment of cancers deficient in
mismatch repair. The FEBS Journal, 282, S1, 115-116, 2015.
Uluslararası bilimsel toplantılarda sunulan ve bildiri kitabında basılan bildiriler
1. Muftuoglu M, Dalmizrak O, Elibol B, Ercan A, Kulaksiz G, Ogus IH, Dalkara T,
and Ozer N. Mitochondrial enzyme activities and mtDNA polymorphisms in
Parkinson`s disease. 13th Balkan Biochemical Biophysical Days and Meeting on
Metabolic Disorders, 28 (3), p.78, OP-3, Kusadası, Izmir, Turkey, 2003.
2. Opresko PL, Muftuoglu M, Wilson DM, and Bohr VA. Telomeric protein TRF2
stimulations DNA synthesis by DNA Polymerase β. Gordon Conference on DNA
Damage, Mutations and Cancer, Venture, CA, 2005.
3. Beck G, Lee JW, Muftuoglu M, and Bohr VA. Mapping of the Werner helicase
single strand annealing activity. 2nd Baltimore Area Repair Symposium: DNA
damage and repair in Cancer, Baltimore, USA, 2006.
4. Hashiguchi K, Hu J, Maynard S, Muftuoglu M, Souza-Pinto N, and Bohr VA.
OGG1 and RAD52 cooperate to repair oxidative DNA damage. 2nd Baltimore
Area Repair Symposium: DNA damage and repair in Cancer, Baltimore, USA,
2006.
5. Wong HK, Muftuoglu M, Beck G, May A, and Bohr VA. Cooperation of Ape1
and CSB in repair of abasic sites. 2nd Baltimore Area Repair Symposium: DNA
damage and repair in Cancer, Baltimore, USA, 2006.
6. Cheng W, Muftic D, Muftuoglu M, Helleday T, Shiloh Y, and Bohr VA. S-phase
checkpoint mediated by WRN-dependent ATM activation. 2006 Internationsl
Workshop on Ataxia-Telangiectasia (A-T) and ATM, P17, Oral presentation,
Banff, Canada, 2006.
7. Bohr VA, Opresko P, Mason P, Muftuoglu M, Kusumoto R, and Cheng W.
Werner and DNA repair at the telomere end. RecQ helicases and other helicases in
telomere maintenance and related pathways. International workshop, Lansdowne,
VA, USA, 2006.
8. Muftuoglu M, Opresko P, and Bohr VA. TRF2 stimulates polymerase beta DNA
synthesis at telomeric and nontelomeric substrates. RecQ helicases and other
helicases in telomere maintenance and related pathways. International workshop,
Lansdowne, VA, USA, 2006.
9. Aydın D, Muftuoglu M and Erman B. Identifying small molecule inhibitors
targeting base excision repair enzymes DNA polymerase gamma and beta to
increase the effect of cancer treatment RECOMB 2012, Barcelona, Spain, 2012.
10. Guven Maiorov E, Keskin O, Muftuoglu M, Gursoy A. Designing and
characterizing small molecule inhibitor(s) for mitochondrial transcription factor A
(TFAM) for therapeutic benefit of Cancer. International Conference and Exhibition
on Computer Aided Drug Design & QSAR. October 29-31, 2012, Chicago-North
Shore, USA.
6.3 Yazılan uluslararası kitaplar veya kitaplarda bölümler
1. Ogus I H, Balk M, Aksoy Y, Muftuoglu M, and Ozer N. The effects of oxidative
stress on the redox system of the human erythrocytes. Free radicals, oxidative
stress and antioxidants, Pathological and physiological significance preceedings,
NATO ASI Series, Plenum Publishing Corporation, New York 25-37, 1998.
2. Muftuoglu M and Bohr VA. Roles of Cockayne syndrome group B protein in
processing oxidative DNA damage and in protection against neurodegeneration.
Molecular Mechanisms of Cockayne Syndrome, Landes Bioscience, Texas, USA,
July 22, 53-63, 2009.
3. Cheng WH, Muftuoglu M, Wu RTY. Selenium and epigenetic effects on histone
marks and DNA methylation. Nutrition and Epigenetics. CRC Press, Taylor and
Francis Group, New York USA. Chp 10, 273-299, 2014.
4. Oktay Y, Agirbasli D, Dalva-Aydemir S, Akyerli-Boylu C, Muftuoglu M,
Yakicier C. Medical Genetics, Current Applications of Biotechnology. Chp 19,
299-317, 2014.
6.4 Ulusal hakemli dergilerde yayınlanan makaleler
1. Muftuoglu M and Ozer N. The in vitro effects of the antimalarial drug primaquine, on
the activities of some enzymes in human erythrocytes lyzates. Turk J Med Sciences, 29,
409-412, 1999.
2. Muftuoglu M, DNA tamiri ve erken yaşlanma sendromları. Turk Biyokimya Dergisi,
28 (1), 20-24, 2003.
6.5 Ulusal bilimsel toplantılarda sunulan ve bildiri kitabında basılan bildiriler
1. Muftuoglu M and Ozer N. The in vitro effects of the antimalarial drug primaquine,
on the activities of catalase, superoxide dismutase, and glucose 6-phosphate
dehydrogenase in human erythrocytes. XIII. National Biochemistry Congress, (with
international participation)/ B07, Turkey, 1996.
2. Ozer N, Muftuoglu M, Ataman D, Ercan A, and Ogus IH. A new and simple
method for the purification of xanthine oxidase from cow milk, XIV. National
Congress of Biochemistry and Symposium on Automation in Clinical Laboratory,
(with international participation)/ B206, Turkey, 1997
3. Muftuoglu M and Ozer N. The in vitro effects of the antimalarial drug primaquine,
on the activities of some enzymes in human erythrocyte lyzates. XIV. National
Congress of Biochemistry and Symposium on Automation in Clinical Laboratory,
(with international participation)/ C335, Turkey, 1997.
4. Ozer N, Muftuoglu M, and Ogus IH. A simple and sensitive method for the activity
staining of xanthine oxidase on polyacrylamide gels. XIV. National Congress of
Biochemistry and Symposium on Automation in Clinical Laboratory, (with
international participation)/ C112, Turkey, 1997.
5. Muftuoglu M, Dalmizrak O, Ogus IH, and Ozer N. The effects of oxidative agents
on mitochondrial heteroplasmy and electron transport chain complex I activity. 1 st
National Molecular Genetic in Diagnosis Congress. P28, Adana, Turkey, 2002.
6. Dalmizrak O, Kulaksiz G, Ercan A, Muftuoglu M, Ogus IH, Cavdar L, Inan L,
Terzioglu A, and Ozer N. The evaluation of mitochondrial complex I and IV
enzyme activities in muscle biopsies of patients with idiopathic PD. National
Congress of Biochemistry, 29 (1), 38-39, SB37, Trabzon, Turkey, 2004.
6.6 Diğer yayınlar
Yazılan ulusal kitap bölümü
Ozer N and Muftuoglu M. Gen Yapısı ve Bilgi İçeriği. Biyoinformatik- I
Lisansüstü Yaz Okulu Kitabı, 41-50, 2003.
Kitap bölümü çevirileri
1. The Art of Medicine (Anderson J, Barnes E, Shackleton, welcome collection), Hiber
Tıp Yayınları, 2012.
2. Biochemistry textbook (Stryer L; Seventh ed. 2010), Chp 29, RNA synthesis and
Processing, Palme yayınevi, Ankara, 2013.
Atıflar
Google Scholar’a göre: Atıflar: 1053, h-endeksi: 18
7. Projeler
1. Oksidatif ajanlarin Memeli Mitokondri DNA`si Üzerindeki Etkileri ve Bu etkilerin
Mitokondriyel Heteroplazmi ve Yaslanma ile Iliskilerinin Arastirilmasi. TUBITAK
projesi, proje no: TBAG-1754, Araştırmacı, 2002.
2. Parkinson Hastaliginda Mitokondriyel DNA mutasyonlarinin belirlenmesi.
Hacettepe Universitesi, Bilimsel Arastirmalar Birimi Projesi. Proje no.
0002101001, Araştırmacı, 2002.
3. Parkinsonlu Hastalarda Mitokondriyel ND2 ve ND4 Mutasyonlarinin ve Gen
Expresyon Duzeylerinin Saptanarak Kompleks I aktivitesi ile ilişkisinin
Arastirilmasi. TUBITAK Projesi. Proje No. SBAG- 2596, Yardımcı Yürütücü,
2004.
4. Idiyopatik Parkinson Hastalarinin Kas Dokusunda, Mitokondriyel Solunum Zinciri
Enzim Duzeylerinin ve mtDNA Mutasyonlarinin Belirlenmesi. Hacettepe
Universitesi, Bilimsel Arastirmalar Birimi Projesi. Proje no. 02G112, Araştırmacı,
2005.
5. SIRT1 mediated protection of mitochondrial biogenesis in Cockayne syndrome B
protein deficient cells upon oxidative stress. Nordea Foundation, Kopenhag,
Danimarka, Proje no: 29068, Proje Yürütücüsü, 2009-2011.
6. Özgün İlaç Keşfi, İlaç Geliştirilmesi ve İstanbul İlaç Sektörü’ne Bilgi ve Teknoloji
Aktarma Amaçlı Bir-Teknoloji Merkezi ve Üniversite-Sanayi İşbirliği Ağının
Kurulması. Istanbul Kalkınma Ajansı (ISTKA) projesi, BIL123, Ortak, 2013-2014.
7. Kanser tedavisine yönelik DNA polimeraz gamma enzimini hedefleyerek
mitokondriyel baz eksizyon tamir mekanizmasını bloke eden küçük molekül
inhibitörlerinin belirlenmesi ve etkinliklerinin saptanması. TÜBİTAK 1001 projesi,
TBAG:212T026, Proje yürütücüsü, 2014-2016.
8. Sporadik Alzheimer hastalığı için yeni bir genetik risk faktörü olarak baz eksizyon
tamir genlerinin genetik varyantlarının taranması ve değerlendirilmesi. TUBİTAK
1001 projesi, KBAG114Z875, Proje yürütücüsü, 2015-2018.
9. Özgün 2-indolinon bileşiklerinin anti-interlökin 1 ve kemoterapötik ilaçlar olarak
geliştirilmesi/DNA tamir inhibitörlerinin polipsiz kalıtsal kolon kanseri (MLH1 gen
defekti) tedavisi için yeni bir ilaç olarak geliştirilmesi. TÜBİTAK 1003, Proje
Yürütücüsü, 2015-2018.
8. İdari Görevler
Fen-Edebiyat Fakültesi Dekan Yardımcısı
Erasmus Fakülte Koordinatörü
9. Bilimsel Kuruluşlara Üyelikler
1. Türk Biyokimya Derneği
2. Federation of European Biochemical Societies
3. DNA Repair Interest Group
4. Mitochondria Interest Group
10. Ödüller
1. NIH visiting fellowship, Ruth L. Kirschstein National Research Service Award
(NRSA) (2004-2009)
2. International Academy of Achievement Summit (2005)
3. NIH Fogarty scholarship (09/1999-06/2000)
4. TUBITAK NATO A2 bursu (04-08/1999)
11. Son iki yılda verdiğiniz lisans ve lisansüstü düzeydeki dersler için aşağıdaki tabloyu
doldurunuz.
Lisans düzeydeki dersler
Dönem
Akademik
Bölüm
Yıl
Güz
2012-2013
İlkbahar
2014-2015
2014-2015
Güz
İlkbahar
Toplam saat
Teorik
Uygulama
Dönem II, 1. Ders
17
8
Kurulu, MEDI201
Biyokimya
Koç
Dönem II, 2. Ders
16
Üniversitesi Kurulu, MSKL202
Tıp Fakültesi Biyokimya
Dönem II, 3. Ders
12
8
Kurulu, BLDI203
Biyokimya
Dersin Adı
Dönem II, 5. Ders
Kurulu, NUTI205
Koç
Biyokimya
Üniversitesi
Dönem II, 6. Ders
Tıp Fakültesi
Kurulu, ERUS206,
Biyokimya
Acıbadem
Üniversitesi,
Moleküler
Biyoloji ve
Genetik
Bölümü
Acıbadem
Üniversitesi,
Moleküler
Biyoloji ve
Genetik
Bölümü
Yüksek lisans düzeydeki dersler
Dönem
Akademik
Bölüm
Yıl
Koç
Üniversitesi
2012-2013 İlkbahar
Sağlık
Bilimleri
Enstitüsü
Acıbadem
Üniversitesi,
Biyokimya ve
2014-2015 İlkbahar
Moleküler
Biyoloji
Lisansüstü
Programı
Öğrenci
Sayısı
32
32
32
12
3
32
17
-
32
MBG201-Hücre
Moleküler
Biyolojisi I
42
28
4
MBG202- Hücre
Moleküler
Biyolojisi II
42
28
4
Dersin Adı
Toplam saat
Teorik
Uygulama
Öğrenci
Sayısı
Biyokimyada özel
konular
(HSBM453)
13
130
1
BMB-627-DNA
Onarımı ve
Mutagenezi
42
-
2